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Green Tea and Milk Thistle to Colorectal Cancer Patients

November 21, 2019


Colorectal cancer is the third most common form of cancer found in the United States, and surgical resection (removal) provides the best chance for cure. Unfortunately,  tumor recurrences develop in 30-40% of patients, and there is evidence suggesting that tumor growth is stimulated after surgery for a period of time. This study focuses on the oral administration of a green tea extract and a milk thistle extract during the week immediately before and weeks after surgery. The goal is that the combination of these two extracts should help to inhibit cancer growth in the days leading up to and following surgery.


Study Information

This clinical trial will have an estimated enrollment of 30 participants. The primary purpose is treatment. The study began in July 2011 and aims to be completed by November 2020.


Inclusion Criteria


  • Patients must be age 18 to 85 years
  • Patient must have biopsy proven colon or rectal cancer
  • Cancer should be judged to be stage 1 to 3 based on preoperative staging
  • Patients may be any race and any gender


Exclusion Criteria


  • Patients with cancer judged to be stage 4 are not eligible
  • Patients undergoing emergency surgery for cancer are not eligible
  • Patients who are immunosuppressed or taking immunosuppressive medications (steroids or chemotherapeutic agents) are not eligible
  • Patients with Crohn’s disease or ulcerative colitis are not eligible
  • Patients with other malignancies are not eligible
  • Patients who are taking part in other neoadjuvant and early adjuvant chemotherapy trials are not eligible



This study is taking place at Mount Sinai St. Luke’s Roosevelt Hospital Center, New York, New York, United States, 10019. For further information, please contact Richard L Whelan, MD on (212) 523-8172 or at


This study is sponsored by Richard Whelan and St. Luke’s-Roosevelt Hospital Center. Richard L Whelan, MD is the Principal Investigator.

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